The NFL's "Best Bets" of Week 10

 The NFL's Week 10 "Best Bets"

Jacksonville Jaguars vs. Kansas City Chiefs

The Jaguars won last Sunday 27-20 over the Los Angeles Chargers to disrupted a five-game losing streak in they last five outings. Jacksonville was 0-2 (SU and ATS) has a underdogs in its last two road games. Kansas City went 3-1 SU at home this season and the only loss was to Buffalo.

Jackson is 0-5 SU against Kansas both at home and on the road in the last five matchups. The Chiefs have the most points in the AFC and the Jaguars have allowed an average of 30.3 points in three of their four road games. The best bet is Kansas City laying the 9.5 points at home. 

Arizona Cardinals vs. Los Angeles Rams

The Cardinals lost 20-12 to the Rams in late September as 3.5-point home underdogs. Arizona is 2-4 SU in the last six road games against Los Angeles. While neither team has been lighting up the scoreboard lately, the Rams own the Cardinels going 9-1 SU (8-1-1 ATS) in the last 10 meetings overall.

With only six combined wins, Arizona and LA are riding out the string on this season. The best bet is the Rams winning the game SU on the money line at home (-124 at FanDuel) instead of covering the 1.5-point spread.  

Los Angeles Chargers vs. San Francisco 49ers

The Chargers are 4-1 SU in they last five games and the 49ers are 3-2 both SU and ATS in the same time frame. Los Angeles has taken the total OVER in four of the last six games and San Francisco's total has gone OVER in three of the last four contests.

The total has gone OVER in eight of the last 11 games between these two interconfernse teams. Los Angeles and San Francisco are both featuring the running game but passing is a option with Justin Herbert (the Chargers) and Jimmy Garoppolo (the 49ers) both at quarterback. The best bet is taking the OVER on 45.5 points in a three-point game either way.